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Kirsi Rilla Selected Research

Hyaluronan Synthases

1/2019Activated hyaluronan metabolism in the tumor matrix - Causes and consequences.
6/2018Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas.
11/2016High extent of O-GlcNAcylation in breast cancer cells correlates with the levels of HAS enzymes, accumulation of hyaluronan, and poor outcome.
9/2015Hyaluronan synthase 3 (HAS3) overexpression downregulates MV3 melanoma cell proliferation, migration and adhesion.
1/2014Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival.
8/2013Hyaluronan production enhances shedding of plasma membrane-derived microvesicles.
9/2010Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma.
5/2009Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content.

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Kirsi Rilla Research Topics

Disease

21Neoplasms (Cancer)
01/2022 - 05/2009
8Inflammation (Inflammations)
04/2020 - 02/2012
6Breast Neoplasms (Breast Cancer)
01/2022 - 01/2014
3Carcinoma (Carcinomatosis)
01/2019 - 05/2009
3Carcinogenesis
01/2019 - 02/2012
3Melanoma (Melanoma, Malignant)
01/2016 - 12/2012
2Joint Diseases (Joint Disease)
05/2022 - 03/2021
2Prostatic Neoplasms (Prostate Cancer)
12/2021 - 01/2017
2Alzheimer Disease (Alzheimer's Disease)
11/2020 - 11/2017
2Hepatocellular Carcinoma (Hepatoma)
04/2020 - 01/2019
2Obesity
11/2016 - 01/2014
2Wounds and Injuries (Trauma)
03/2013 - 02/2012
2Hyperplasia
10/2011 - 09/2010
2Macular Degeneration (Age-Related Maculopathy)
07/2010 - 09/2009
1Hemolysis
05/2021
1Osteoarthritis
03/2021
1Rheumatoid Arthritis
03/2021
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2020
1Non-alcoholic Fatty Liver Disease
04/2020
1Fatty Liver
04/2020
1Lipidoses
04/2020
1Glioma (Gliomas)
01/2020
1Liver Diseases (Liver Disease)
01/2019
1Brain Diseases (Brain Disorder)
01/2019
1Astrocytoma (Pilocytic Astrocytoma)
06/2018
1Disease Progression
06/2018
1Mitochondrial Diseases (Mitochondrial Disease)
08/2017
1Malignant Mesothelioma
10/2016
1Mesothelioma
10/2016
1Pleural Effusion (Pleural Effusions)
10/2016
1Adenocarcinoma of Lung
10/2016
1Adenocarcinoma
10/2016
1Chondrosarcoma
03/2015
1Chromosome Aberrations (Chromosome Abnormalities)
09/2013
1Aneuploidy (Aneuploid)
09/2013
1Cysts
08/2013
1Erythema
10/2011
1Endometrial Neoplasms (Endometrial Cancer)
09/2010
1Endometrioid Carcinoma
09/2010
1Ovarian Neoplasms (Ovarian Cancer)
05/2009
1Starvation
09/2005
1Hypertrophy
10/2004

Drug/Important Bio-Agent (IBA)

25Hyaluronic Acid (Hyaluronan)IBA
01/2022 - 10/2004
8Hyaluronan SynthasesIBA
01/2019 - 05/2009
6Proteins (Proteins, Gene)FDA Link
11/2017 - 05/2009
5GlycosaminoglycansIBA
01/2022 - 10/2016
5EnzymesIBA
01/2019 - 01/2014
4Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2014
3Glucose (Dextrose)FDA LinkGeneric
01/2019 - 01/2016
2LipidsIBA
05/2022 - 04/2020
2Biological ProductsIBA
01/2021 - 09/2013
2Uridine Diphosphate (UDP)IBA
01/2019 - 01/2016
2MicroRNAs (MicroRNA)IBA
01/2019 - 09/2013
2SugarsIBA
01/2019 - 01/2016
2Hyaluronan ReceptorsIBA
10/2016 - 10/2011
2Hyaluronoglucosaminidase (Hyaluronidase)FDA Link
09/2015 - 05/2009
2Phosphotransferases (Kinase)IBA
09/2015 - 12/2012
2CytokinesIBA
05/2015 - 03/2013
2Polysaccharides (Glycans)IBA
10/2011 - 05/2009
2Messenger RNA (mRNA)IBA
09/2010 - 05/2009
2Retinal Pigments (Pigments, Visual)IBA
07/2010 - 09/2009
1Prostate-Specific Antigen (Semenogelase)IBA
12/2021
1ElementsIBA
12/2021
1Peptides (Polypeptides)IBA
05/2021
1Trastuzumab (Herceptin)FDA Link
01/2021
1Pharmaceutical PreparationsIBA
01/2021
1Amyloid (Amyloid Fibrils)IBA
11/2020
1Orotic AcidIBA
04/2020
1LipopolysaccharidesIBA
04/2020
1Lipoproteins (Lipoprotein)IBA
04/2020
1Fatty Acids (Saturated Fatty Acids)IBA
04/2020
1EndotoxinsIBA
04/2020
1HydrolasesIBA
01/2020
1Serine (L-Serine)FDA Link
01/2020
1LigandsIBA
01/2019
1Free RadicalsIBA
01/2019
1Cell Surface ReceptorsIBA
06/2018
1CholesterolIBA
11/2017
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2017
1IsoenzymesIBA
10/2016
1OligosaccharidesIBA
09/2015
1taurine transporterIBA
03/2015
1enhanced green fluorescent proteinIBA
03/2015
1Indicators and Reagents (Reagents)IBA
01/2014
1Estrogen ReceptorsIBA
01/2014
1IntegrinsIBA
09/2013
1Mannose (D-Mannose)IBA
03/2013
1CollagenIBA
12/2012
1Conditioned Culture MediaIBA
12/2012
1Matrix Metalloproteinases (MMPs)IBA
12/2012
1Small Interfering RNA (siRNA)IBA
12/2012
1ParaffinIBA
09/2010
1LipofuscinIBA
09/2009
1Uridine Diphosphate Glucuronic Acid (UDP Glucuronic Acid)IBA
09/2005
1Epidermal Growth Factor (EGF)IBA
10/2004

Therapy/Procedure

1Knee Replacement Arthroplasty (Total Knee Replacement)
03/2021
1Therapeutics
01/2014